Publications

2017

DM DeLorenzo, WR Henson and TS Moon. Development of Chemical and Metabolite Sensors for Rhodococcus opacus PD630. ACS Synth. Biol. Accepted. DOI: 10.1021/acssynbio.7b00192
http://pubs.acs.org/doi/abs/10.1021/acssynbio.7b00192

T Shopera, WR Henson and TS Moon. Dynamics of sequestration-based gene regulatory cascades. Nucleic Acids Res. DOI: 10.1093/nar/gkx465
https://academic.oup.com/nar/article/3835315/Dynamics-of-sequestration-based-gene-regulatory

T Shopera, L He, T Oyetunde, YJ Tang and TS Moon. Decoupling resource-coupled gene expression in living cells. ACS Synth. Biol. Accepted. DOI: 10.1021/acssynbio.7b00119
http://pubs.acs.org/doi/abs/10.1021/acssynbio.7b00119

TS Moon. What Is the Role of Circuit Design in the Advancement of Synthetic Biology? Cell Systems 4, 370-372 (with 8 other contributors).
http://www.cell.com/cell-systems/fulltext/S2405-4712(17)30135-7

N Wan, DM DeLorenzo, L He, L You, CM Immethun, G Wang, EEK Baidoo, W Hollinshead, JD Keasling, TS Moon and YJ Tang. Cyanobacterial carbon metabolism: fluxome plasticity and oxygen dependence. Biotechnol. Bioeng. Accepted. DOI: 10.1002/bit.26287
http://onlinelibrary.wiley.com/doi/10.1002/bit.26287/full

A Hoynes-O’Connor, T Shopera, K Hinman, JP Creamer and TS Moon. Enabling Complex Genetic Circuits to Respond to Extrinsic Environmental Signals. Biotechnol. Bioeng. Accepted. DOI: 10.1002/bit.26279
http://onlinelibrary.wiley.com/doi/10.1002/bit.26279/full

CM Immethun, DM DeLorenzo, CM Focht, D Gupta, CB Johnson and TS Moon. Physical, Chemical, and Metabolic State Sensors Expand the Synthetic Biology Toolbox for Synechocystis sp. PCC 6803. Biotechnol. Bioeng. Accepted. DOI: 10.1002/bit.26275
http://onlinelibrary.wiley.com/doi/10.1002/bit.26275/full

2016

A Hoynes-OConnor and TS Moon. Development of design rules for reliable antisense RNA behavior in E. coliACS Synth. Biol. 5, 1441−1454 (2016). Featured on the Cover Page
http://pubs.acs.org/doi/abs/10.1021/acssynbio.6b00036

Cover

R Saha, D Liu, A Hoynes-O'Connor, M Liberton, J Yu, M Bhattacharyya-Pakrasi, A Balassy, F Zhang, TS Moon, CD Maranas and HB Pakrasi. Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Insights from Transcriptomic, Fluxomic and Physiological Analyses. mBio. 7, e00464-16 (2016)
http://mbio.asm.org/cgi/content/abstract/mBio.00464-16

CM Immethun, WR Henson, X Wang, D Nielsen and TS Moon. Engineering Central Metabolism for Production of Higher Alcohol-based Biofuels, Chapter 1, p1-34 in "Biotechnologies for Biofuel Production and Optimization" (CA Eckert & CT Trinh, Ed). Elsevier. 
http://dx.doi.org/10.1016/B978-0-444-63475-7.00001-7

YJ Lee, A Hoynes-O'Connor, MC Leong and TS Moon. Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system. Nucleic Acids Res. DOI: 10.1093/nar/gkw056 (2016)
One of NAR Top Articles (most often accessed in July 2017)
http://nar.oxfordjournals.org/content/early/2016/02/01/nar.gkw056.full

A Yoneda, WR Henson, NK Goldner, KJ Park, KJ Forsberg, SJ Kim, MW Pesesky, M Foston, G Dantas and TS Moon. Comparative transcriptomics elucidates adaptive phenol tolerance and utilization in lipid-accumulatingRhodococcus opacus PD630. Nucleic Acids Res. DOI: 10.1093/nar/gkw055 (2016)
http://nar.oxfordjournals.org/content/early/2016/02/01/nar.gkw055.full

2015

T Shopera, WR Henson, A Ng, YJ Lee, K Ng and TS Moon. Robust, tunable genetic memory from protein sequestration combined with positive feedback. Nucleic Acids Res. DOI: 10.1093/nar/gkv936 (2015)
http://nar.oxfordjournals.org/content/early/2015/09/17/nar.gkv936.full

CM Immethun, KM Ng, DM DeLorenzo, B Waldron-Feinstein, YC Lee and TS Moon. Oxygen-Responsive Genetic Circuits Constructed in Synechocystis sp. PCC 6803. Biotechnol. Bioeng. DOI: 10.1002/bit.25722 (2015)
http://onlinelibrary.wiley.com/doi/10.1002/bit.25722/abstract

WD Hollinshead, WR Henson, Mary Abernathy, TS Moon, and YJ Tang. Rapid Metabolic Analysis of Rhodococcus opacus PD630 via parallel 13C-Metabolite Fingerprinting. Biotechnol. Bioeng. DOI: 10.1002/bit.25702 (2015)...
http://onlinelibrary.wiley.com/doi/10.1002/bit.25702/abstract

A Hoynes-O’Connor and TS Moon. Programmable genetic circuits for pathway engineering. Curr. Opin. Biotechnol. 36, 115-121 (2015).
http://www.sciencedirect.com/science/article/pii/S0958166915001068

A Hoynes-O’Connor, K Hinman, L Kirchner and TS Moon. De novo design of heat-repressible RNA thermosensors in E. coli. Nucleic Acids Res. 43, 6166–6179 (2015)
http://nar.oxfordjournals.org/content/43/12/6166

2014

B Thompson, TS Moon and D Nielsen. ‘Hybrid’ Processing Strategies for Expanding and Improving the Synthesis of Renewable Bioproducts, Curr. Opin. Biotechnol. 30, 17-23 (2014).
http://dx.doi.org/10.1016/j.copbio.2014.04.005

2013

D Nielsen and TS Moon. From Promise to Practice: the Role of Synthetic Biology in Green Chemistry, EMBO Reports, published online, doi:10.1038/embor.2013.178 (2013)
http://dx.doi.org/10.1038/embor.2013.178

BM Berla, R Saha, CM Immethun, CD Maranas, TS Moon and H Pakrasi. Synthetic Biology of Cyanobacteria: Unique Challenges and Opportunities, Front. Microbiol. 4:246 (2013)
http://www.frontiersin.org/Microbial_Physiology_and_Metabolism/10.3389/fmicb.2013.00246/abstract

K Solomon, TS Moon, B Ma, TM Sanders and KJ Prather. Tuning primary metabolism for heterologous pathway productivity, ACS Synth. Biol. 2, 126-135 (2013)
http://dx.doi.org/10.1021/sb300055e
Professor Moon is highlighted in ACS Synthetic Biology's "Introducing Our Authors".
http://pubs.acs.org/doi/full/10.1021/sb400018u

CM Immethun, AG Hoynes-O’Connor, A Balassy and TS Moon. Microbial Production of Isoprenoids Enabled by Synthetic Biology, Front. Microbio. 4 (75), Invited review (2013)
http://www.frontiersin.org/microbiotechnology,_ecotoxicology_and_bioremediation/10.3389/fmicb.2013.00075/abstract

2012

TS Moon, C Lou, A Tamsir, BC Stanton and CA Voigt. Genetic Programs Constructed from Layered Logic Gates in Single Cells, Nature. 491, 249-253 (2012)
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11516.html

TS Moon*, D Nielsen* and KJ Prather. Sensitivity Analysis of a Proposed Model Mechanism for Newly Created Glucose 6-Oxidases, AIChE J. 58, 2303-2308 (2012)
http://dx.doi.org/10.1002/aic.12762

2011

TS Moon, EJ Clarke, ES Groban, A Tamsir, RM Clark, M Eames, T Kortemme and CA Voigt. Construction of a genetic multiplexer to toggle between chemosensory pathways in Escherichia coli, J. Mol. Biol. 406, 215-227 (2011)
http://dx.doi.org/10.1016/j.jmb.2010.12.019

2010

SM Lippow*, TS Moon*, S Basu, S-H Yoon, X Li, B Chapman, K Robison, D Lipovšek and KJ Prather. Engineering enzyme specificity using computational design of a defined-sequence library, Chem. Biol. 17, 1306-1315 (2010)
Selected as a “Recommended” paper by faculty of 1000
http://dx.doi.org/10.1016/j.chembiol.2010.10.012

TS Moon, JE Dueber, E Shiue and KJ Prather. Use of Modular, Synthetic Scaffolds for Improved Production of Glucaric Acid in Engineered E. coli, Metab. Eng. 12, 298-305 (2010)
http://dx.doi.org/10.1016/j.ymben.2010.01.003

2009

JE Dueber, GC Wu, GR Malmirchegini, TS Moon, CJ Petzold, AV Ullal, KJ Prather and JD Keasling. Synthetic Protein Scaffolds Provide Modular Control over Metabolic Flux, Nat. Biotechnol. 27, 753-759 (2009)
http://dx.doi.org/ 10.1038/nbt.1557

TS Moon, S-H Yoon, M-J Tsang Mui Ching, A Lanza and KJ Prather. Enzymatic assay of D-glucuronate using uronate dehydrogenase, Anal. Biochem. 392, 183-185 (2009)
http://dx.doi.org/10.1016/j.ab.2009.05.032

S-H Yoon, TS Moon, P Iranpour, A Lanza and KJ Prather. Cloning and characterization of uronate dehydrogenases from two Pseudomonads and Agrobacterium tumefaciens str. C58, J. Bateriol. 191, 1565-1573 (2009)
http://dx.doi.org/10.1128/JB.00586-08

TS Moon, S-H Yoon, A Lanza, J Roy-Mayhew and KJ Prather. Production of glucaric acid from a synthetic pathway in recombinant Escherichia coli, Appl. Environ. Microbiol. 75, 589-595 (2009)
http://dx.doi.org/10.1128/AEM.00973-08

2005

SH Kim, K Hyun, TS Moon, T Mitsumata, JS Hong, KH Ahn and SJ Lee. Morphology-rheology relationship in hyaluronate/poly(vinyl alcohol)/borax polymer blends, Polymer, 46, 7156-7163 (2005)
http://dx.doi.org/10.1016/j.polymer.2005.05.089

*These authors contributed equally to the work.

Patents

  • C Lou, TS Moon, V Rhodius, B Stanton, A Tamsir, K Temme and CA Voigt, Synthetic Biology Tools, US patent application (2011)

  • TS Moon, KJ Prather and K Solomon, Glucose Valve and Other Metabolite Valves, US patent application (2010)

  • TS Moon, S-H Yoon and KJ Prather, Cellular Production of Glucaric Acid, US patent application US2011/0124065 A18 (2008)

  • TS Moon, JH Kim, JY Lee, BH Min and KY Cho, Hyaluronic Acid Derivative Gel and Method for Preparing the Same, PCT Int. Appl. WO04/011503 (2004)

  • KY Cho, JH Kim, JY Lee, TS Moon and BH Min, Microbeads of Natural Polysaccharide and Hyaluronic Acid and Processes for Preparing the Same, PCT Int. Appl. WO04/020473 (2004)

  • KY Cho, JH Kim, JY Lee, TS Moon and BH Min, Hyaluronic Acid Derivatives and Processes for Preparing the Same, PCT Int. Appl. WO04/022603 (2004)

  • TS Moon, JY Lee, JH Kim and KB Han, Crosslinked Amide Derivatives of Hyaluronic Acid and Manufacturing Method Thereof, PCT Int. Appl. WO02/030990 (2002)

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