Our research goals are directed towards programmable cells that process multiple input signals to produce desirable outputs for real world applications. Specifically, we aim to build synthetic gene circuits in order to control and improve metabolic pathways for the production of biomass-based chemicals and drugs. Learn more
Tae Seok Moon
Postdoctoral research at MIT and University of
California-San Francisco provided Dr. Moon with
expertise in the design and construction of genetic
circuits. As a graduate student at MIT, he learned
how to construct and optimize novel metabolic
pathways to produce biochemicals that can replace
oil-based chemicals. Combining his research
experiences with more than five years experience in
the biotechnology industry, he envisions his career
as transforming biology research from an
"observation" approach to a "synthesis-based
engineering" activity to address energy, environment
and health issues. Learn more
about Dr. Moon
Cheryl gave a poster presentation at the 12th Workshop on Cyanobacteria at ASU.
Our collaborative work (with the Pakrasi, Maranas, and Zhang labs) was published: R Saha, D Liu, A Hoynes-O'Connor, M Liberton, J Yu, M Bhattacharyya-Pakrasi, A Balassy, F Zhang, TS Moon, CD Maranas and HB Pakrasi. Diurnal Regulation of Cellular Processes in the Cyanobacterium Synechocystis sp. Strain PCC 6803: Insights from Transcriptomic, Fluxomic and Physiological Analyses. mBio. 7, e00464-16 (2016) Link
Cheryl, Ray, Tatenda, Allison, and Ryan gave five poster presentations at the Monsanto Fellows Synthetic Biology Symposium.
Matthew Leong receives a 2016 BioSURF Fellowship. Congratulations, Matthew!
Andrew Ng (Moon lab alumnus, now at UC Berkeley/UCSF) receives a 2016 National Defense Science and Engineering Graduate (NDSEG) Fellowship. Congratulations, Andrew!
Ryan wins an oral presentation award at the SynBERC meeting at UC Berkeley. Congrats, Ryan!
Ryan gave an oral presentation at the SynBERC meeting at UC Berkeley. Allie also gave a poster presentation.
Professor Moon gave three oral presentations at the 251st ACS National Meeting. One of the presentations was identified as the "Best Presentation" of the Session.
Congratulations to Cheryl for receiving a Registration Scholarship for the 12th Workshop on Cyanobacteria at ASU.
Congratulations to Cheryl for her book chapter published: CM Immethun, WR Henson, X Wang, D Nielsen and TS Moon. Engineering Central Metabolism for Production of Higher Alcohol-based Biofuels, Chapter 1, p1-34 in "Biotechnologies for Biofuel Production and Optimization" (CA Eckert & CT Trinh, Ed). Elsevier. Link
Congratulations to Ray for his paper accepted: A Yoneda, WR Henson, NK Goldner, KJ Park, KJ Forsberg, SJ Kim, MW Pesesky, M Foston, G Dantas and TS Moon. Comparative transcriptomics elucidates adaptive phenol tolerance and utilization in lipid-accumulating Rhodococcus opacus PD630. Nucleic Acids Res. Link
Cheryl, Ray, Tatenda, and Allison gave oral presentations at the 2015 AIChE annual meeting.
Mike gave a poster presentation in the Undergraduate Research Symposium at WashU.
Professor Moon gave an invited talk at the Washington University Biomedical Engineering Department.
Congratulations to Tatenda for his paper published: T Shopera, WR Henson, A Ng, YJ Lee, K Ng and TS Moon. Robust, tunable genetic memory from protein sequestration combined with positive feedback. Nucleic Acids Res. DOI: 10.1093/nar/gkv936 (2015) Link
Cameron and Eugene join the lab as graduate rotation students! Welcome everyone!
Congratulations to Cheryl for her paper accepted: CM Immethun, KM Ng, DM DeLorenzo, B Waldron-Feintstein, YC Lee and TS Moon. Oxygen-Responsive Genetic Circuits Constructed in Synechocystis sp. PCC6803. Biotechnol. Bioeng. DOI: 10.1002/bit.25722 (2015)
Congratulations to Ray for his paper accepted: WD Hollinshead, WR Henson, M Abernathy, TS Moon and YJ Tang. Rapid Metabolic Analysis of Rhodococcus opacus PD630 via parallel 13C-Metabolite Fingerprinting, Biotechnol. Bioeng. DOI: 10.1002/bit.25702 (2015)
Congratulations to Allison for her paper published online: A Hoynes-O’Connor, K Hinman, L Kirchner and TS Moon. De novo design of heat-repressible RNA thermosensors in E. coli. Nucleic Acids Res. doi: 10.1093/nar/gkv499 (2015). Link
Kenneth gave a poster presentation at the 3rd Annual Global Health and Infectious Disease Conference.
Ray gave a featured oral presentation at the 2015 Annual Conference for the Institute for Biological Engineering.
Cheryl, Allison, and Tatenda each gave oral presentations at the Annual IBE Conference.
The 2014 WashU iGEM team gave an oral presentation at the IBE conference.
Professor Moon gave three oral presentations including an invited talk at the 2014 AIChE conference.
Cheryl & Allison gave oral presentations at the 2014 AIChE conference.
Professor Moon gave an invited lecture at the Indo-US Workshop on Synthetic & Systems Biology (JNU, New Delhi, India) to discuss the potential and risks of synthetic biology. https://sites.google.com/site/synbioworkshop/synbioglobal
Wei Bai joins the lab as a graduate rotation student! Welcome!
The WUSTL 2014 iGEM team received a silver medal at the iGEM Giant Jamboree. Congrats to all members involved!
Ray and Tatenda presented posters at the SynBERC meeting at MIT.
Professor Moon gave an invited talk at the SynBERC meeting at MIT.
Drew Delorenzo, Charlie Johnson, Yu He, and Ben Wolf join the lab as graduate rotation students! Welcome everyone!
Allison Hoynes-O'Connor wins a poster presentation award at the 2014 SIMB conference! Congrats, Allison!
Cheryl, Allison, and Ray presented posters at the 2014 SIMB conference.
Professor Moon gave an invited talk at the 2014 Annual Meeting of the Society for Industrial Microbiology & Biotechnology (SIMB), click here for more info.
Professor Moon gave a talk at the inaugural SEED conference (the Synthetic Biology: Engineering, Evolution & Design), click here for more info.
paper published online: B Thompson, TS Moon and D
Nielsen. ‘Hybrid’ Processing Strategies for
Expanding and Improving the Synthesis of Renewable
Bioproducts, Curr. Opin. Biotechnol. 30, 17-23
Allison, Cheryl, and Ray
in the Moon lab received project funding from
Women's Society of Washington University for the
outreach activities which include teaching kit
development for Teach For America Teachers!
Please contact Allie at firstname.lastname@example.org
for more information!
Kenneth Ng joins the lab as a research technician! Welcome Kenneth!
Research Group receives a grant from the National
Science Foundation for "Designing Nitrogen Fixing
Ability in Oxygenic Photosynthetic Cells."
Paper highlighted as Featured Article in
Frontiers in Microbiology!
Moon Research Group
receives an I-CARES Research Award for "Hybrid
Conversion of Lignin: Trees to Fat" with
collaborator Professor Marcus Foston, also from EECE
at Washington University in St. Louis.
Ray Henson, Allison
Hoynes-O'Connor, and Tatenda Shopera join the group
as PhD candidates. Welcome Ray, Allison and
Professor Moon is
highlighted in ACS Synthetic Biology's
"Introducing Our Authors".
CM Immethun, AG Hoynes-O’Connor, A Balassy and TS Moon. Microbial Production of Isoprenoids Enabled by Synthetic Biology, Invited review, accepted in Frontiers in Microbiology.
Ray Henson and Tatenda Shopera join the group as Graduate Rotation students. Welcome Ray and Tatenda!